HCSGD entry for MTMR3
1. General information
| Official gene symbol | MTMR3 |
|---|---|
| Entrez ID | 8897 |
| Gene full name | myotubularin related protein 3 |
| Other gene symbols | FYVE-DSP1 ZFYVE10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004438 | Phosphatidylinositol-3-phosphatase activity | IDA | molecular_function |
| GO:0004722 | Protein serine/threonine phosphatase activity | IDA | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006470 | Protein dephosphorylation | IDA | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0294692185 | 0.9783868280 | 0.3973664447 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0245947847 |
| GSE13712_SHEAR | Up | 0.4706322625 |
| GSE13712_STATIC | Up | 0.0133294232 |
| GSE19018 | Up | 0.1423113826 |
| GSE19899_A1 | Up | 0.1692838374 |
| GSE19899_A2 | Up | 0.3602199651 |
| PubMed_21979375_A1 | Up | 0.5772905634 |
| PubMed_21979375_A2 | Up | 0.4739696265 |
| GSE35957 | Up | 0.1486644966 |
| GSE36640 | Up | 0.6698359296 |
| GSE54402 | Up | 0.1695306673 |
| GSE9593 | Up | 0.2929387413 |
| GSE43922 | Down | -0.0160618996 |
| GSE24585 | Up | 0.3582031911 |
| GSE37065 | Up | 0.1168492768 |
| GSE28863_A1 | Up | 0.7052818139 |
| GSE28863_A2 | Up | 0.3865014305 |
| GSE28863_A3 | Down | -0.4966468583 |
| GSE28863_A4 | Down | -0.2080398216 |
| GSE48662 | Up | 0.2729071519 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT006871 | Luciferase reporter assay | Functional MTI | 22971574 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037294 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038158 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038555 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045920 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046210 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048345 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050972 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
