HCSGD entry for EIF2S2
1. General information
| Official gene symbol | EIF2S2 |
|---|---|
| Entrez ID | 8894 |
| Gene full name | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| Other gene symbols | EIF2 EIF2B EIF2beta PPP1R67 eIF-2-beta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0002176 | Male germ cell proliferation | IEA | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003743 | Translation initiation factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005850 | Eukaryotic translation initiation factor 2 complex | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | TAS | molecular_function |
| GO:0008584 | Male gonad development | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5602811557 | 0.0537192812 | 0.9999902473 | 0.4366976529 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0834221008 |
| GSE13712_SHEAR | Down | -0.0073408039 |
| GSE13712_STATIC | Down | -0.0105584425 |
| GSE19018 | Up | 0.3446672957 |
| GSE19899_A1 | Up | 0.0613557925 |
| GSE19899_A2 | Down | -0.3637286498 |
| PubMed_21979375_A1 | Up | 0.3315120820 |
| PubMed_21979375_A2 | Down | -0.0773796742 |
| GSE35957 | Up | 0.2268032086 |
| GSE36640 | Down | -0.1622111857 |
| GSE54402 | Down | -0.0771395271 |
| GSE9593 | Up | 0.2862073233 |
| GSE43922 | Down | -0.0096618032 |
| GSE24585 | Down | -0.4193438870 |
| GSE37065 | Down | -0.2257163781 |
| GSE28863_A1 | Down | -0.2595338026 |
| GSE28863_A2 | Down | -0.5818993960 |
| GSE28863_A3 | Up | 0.5884175356 |
| GSE28863_A4 | Down | -0.8376617645 |
| GSE48662 | Up | 0.0235498398 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021922 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022382 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028733 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-363-3p | MIMAT0000707 | MIRT044047 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
