HCSGD entry for SYNJ1
1. General information
| Official gene symbol | SYNJ1 |
|---|---|
| Entrez ID | 8867 |
| Gene full name | synaptojanin 1 |
| Other gene symbols | INPP5G |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004439 | Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0004445 | Inositol-polyphosphate 5-phosphatase activity | TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | TAS | biological_process |
| GO:0007612 | Learning | IEA | biological_process |
| GO:0016082 | Synaptic vesicle priming | IEA | biological_process |
| GO:0016191 | Synaptic vesicle uncoating | IEA | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0042578 | Phosphoric ester hydrolase activity | IEA | molecular_function |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046855 | Inositol phosphate dephosphorylation | IEA | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IEA | biological_process |
| GO:0048488 | Synaptic vesicle endocytosis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0393481327 | 0.8919378405 | 0.4466468333 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1578535654 |
| GSE13712_SHEAR | Up | 0.1339280315 |
| GSE13712_STATIC | Up | 0.3224029682 |
| GSE19018 | Down | -0.2500348756 |
| GSE19899_A1 | Up | 0.0448973849 |
| GSE19899_A2 | Up | 0.1562256707 |
| PubMed_21979375_A1 | Up | 0.6652204192 |
| PubMed_21979375_A2 | Up | 0.1496535960 |
| GSE35957 | Up | 0.0259626451 |
| GSE36640 | Up | 0.9462024402 |
| GSE54402 | Up | 0.1112492836 |
| GSE9593 | Down | -0.0888092471 |
| GSE43922 | Up | 0.3621959639 |
| GSE24585 | Up | 0.7412300698 |
| GSE37065 | Up | 0.3978629042 |
| GSE28863_A1 | Up | 0.1461905268 |
| GSE28863_A2 | Up | 0.4915588359 |
| GSE28863_A3 | Down | -0.7814139848 |
| GSE28863_A4 | Up | 0.0368897107 |
| GSE48662 | Down | -0.3819097908 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027224 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028365 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031926 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046396 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047739 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049591 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
