HCSGD entry for LDB1

1. General information

Official gene symbolLDB1
Entrez ID8861
Gene full nameLIM domain binding 1
Other gene symbolsCLIM2 NLI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000790Nuclear chromatinIDAcellular_component
GO:0000972Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear peripheryISSbiological_process
GO:0001102RNA polymerase II activating transcription factor bindingIPImolecular_function
GO:0001158Enhancer sequence-specific DNA bindingIEAmolecular_function
GO:0001702Gastrulation with mouth forming secondIEAbiological_process
GO:0001942Hair follicle developmentIEAbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005634NucleusISScellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006351Transcription, DNA-templatedNASbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0007275Multicellular organismal developmentNASbiological_process
GO:0009948Anterior/posterior axis specificationIEAbiological_process
GO:0010669Epithelial structure maintenanceIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0019899Enzyme bindingIEAmolecular_function
GO:0021702Cerebellar Purkinje cell differentiationIEAbiological_process
GO:0022607Cellular component assemblyIEAbiological_process
GO:0030182Neuron differentiationISSbiological_process
GO:0030274LIM domain bindingIPI ISSmolecular_function
GO:0032784Regulation of DNA-templated transcription, elongationISSbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0043234Protein complexISScellular_component
GO:0043621Protein self-associationIEAmolecular_function
GO:0043973Histone H3-K4 acetylationISSbiological_process
GO:0045647Negative regulation of erythrocyte differentiationISSbiological_process
GO:0045785Positive regulation of cell adhesionIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIMP ISSbiological_process
GO:0046985Positive regulation of hemoglobin biosynthetic processISSbiological_process
GO:0060322Head developmentIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01626929070.90395611110.31376644691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3195586704
GSE13712_SHEARUp0.0414514399
GSE13712_STATICDown-0.1055319658
GSE19018Down-0.1931230067
GSE19899_A1Up0.7274174076
GSE19899_A2Up1.6308482475
PubMed_21979375_A1Up1.2216756190
PubMed_21979375_A2Up3.7416990774
GSE35957Up0.1248035358
GSE36640Up0.9114218437
GSE54402Down-0.1273330795
GSE9593Up0.1905851957
GSE43922Down-0.0197742525
GSE24585Down-0.1527403113
GSE37065Up0.0709001186
GSE28863_A1Up0.0694603251
GSE28863_A2Down-0.0535734627
GSE28863_A3Down-0.0800547462
GSE28863_A4Down-0.1659565243
GSE48662Up0.4402520116

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.