HCSGD entry for PROZ
1. General information
| Official gene symbol | PROZ |
|---|---|
| Entrez ID | 8858 |
| Gene full name | protein Z, vitamin K-dependent plasma glycoprotein |
| Other gene symbols | PZ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0007596 | Blood coagulation | IEA | biological_process |
| GO:0017187 | Peptidyl-glutamic acid carboxylation | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7796421792 | 0.6045672353 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0050431134 |
| GSE13712_SHEAR | Down | -0.0569046416 |
| GSE13712_STATIC | Down | -0.2898454221 |
| GSE19018 | Up | 0.0627405829 |
| GSE19899_A1 | Up | 0.0709705567 |
| GSE19899_A2 | Down | -0.0483523892 |
| PubMed_21979375_A1 | Up | 0.0692336183 |
| PubMed_21979375_A2 | Down | -0.2610310605 |
| GSE35957 | Up | 0.4321910876 |
| GSE36640 | Up | 0.1297878822 |
| GSE54402 | Down | -0.0834495304 |
| GSE9593 | Down | -0.0509468208 |
| GSE43922 | Up | 0.1566987119 |
| GSE24585 | Up | 0.0248508269 |
| GSE37065 | Down | -0.0111046637 |
| GSE28863_A1 | Down | -0.1979636163 |
| GSE28863_A2 | Down | -0.2029289829 |
| GSE28863_A3 | Up | 0.2476710699 |
| GSE28863_A4 | Up | 0.0637112219 |
| GSE48662 | Up | 0.0108935313 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Menadione | DB00170 | NUTR00062 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
