HCSGD entry for AKAP4
1. General information
| Official gene symbol | AKAP4 |
|---|---|
| Entrez ID | 8852 |
| Gene full name | A kinase (PRKA) anchor protein 4 |
| Other gene symbols | AKAP 82 AKAP-4 AKAP82 CT99 FSC1 HI PRKA4 hAKAP82 p82 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0005952 | CAMP-dependent protein kinase complex | NAS | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007178 | Transmembrane receptor protein serine/threonine kinase signaling pathway | IEA | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0008104 | Protein localization | IEA | biological_process |
| GO:0030018 | Z disc | IEA | cellular_component |
| GO:0030030 | Cell projection organization | IEA | biological_process |
| GO:0030317 | Sperm motility | IMP | biological_process |
| GO:0031514 | Motile cilium | IDA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051018 | Protein kinase A binding | ISS | molecular_function |
| GO:0097228 | Sperm principal piece | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6343577676 | 0.6483008472 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0294196616 |
| GSE13712_SHEAR | Up | 0.2090654196 |
| GSE13712_STATIC | Down | -0.0041282724 |
| GSE19018 | Up | 0.0173120246 |
| GSE19899_A1 | Up | 0.0540681031 |
| GSE19899_A2 | Down | -0.0177254720 |
| PubMed_21979375_A1 | Down | -0.1568651467 |
| PubMed_21979375_A2 | Down | -0.1003546378 |
| GSE35957 | Up | 0.2110372783 |
| GSE36640 | Up | 0.1185314506 |
| GSE54402 | Up | 0.0044931385 |
| GSE9593 | Up | 0.1013380983 |
| GSE43922 | Up | 0.0050151692 |
| GSE24585 | Down | -0.0458389468 |
| GSE37065 | Up | 0.0385884789 |
| GSE28863_A1 | Down | -0.3497231291 |
| GSE28863_A2 | Down | -0.1990904118 |
| GSE28863_A3 | Up | 0.0372599532 |
| GSE28863_A4 | Up | 0.0932689631 |
| GSE48662 | Up | 0.4660571809 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022331 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023610 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
