HCSGD entry for ALKBH1
1. General information
| Official gene symbol | ALKBH1 |
|---|---|
| Entrez ID | 8846 |
| Gene full name | alkB, alkylation repair homolog 1 (E. coli) |
| Other gene symbols | ABH ABH1 ALKBH alkB hABH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0001890 | Placenta development | IEA | biological_process |
| GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity | IDA | molecular_function |
| GO:0005719 | Nuclear euchromatin | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006281 | DNA repair | IDA | biological_process |
| GO:0006307 | DNA dealkylation involved in DNA repair | IDA | biological_process |
| GO:0008198 | Ferrous iron binding | IDA | molecular_function |
| GO:0031175 | Neuron projection development | IEA | biological_process |
| GO:0042056 | Chemoattractant activity | IEA | molecular_function |
| GO:0042245 | RNA repair | IDA | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0048589 | Developmental growth | IEA | biological_process |
| GO:0070579 | Methylcytosine dioxygenase activity | IDA | molecular_function |
| GO:0070989 | Oxidative demethylation | IDA | biological_process |
| GO:0080111 | DNA demethylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0476859238 | 0.7818321416 | 0.4823515175 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2996179572 |
| GSE13712_SHEAR | Up | 0.2358568692 |
| GSE13712_STATIC | Down | -0.0095948245 |
| GSE19018 | Down | -0.4282007559 |
| GSE19899_A1 | Up | 0.2536303546 |
| GSE19899_A2 | Up | 0.5982501252 |
| PubMed_21979375_A1 | Up | 0.9155477567 |
| PubMed_21979375_A2 | Up | 1.0422511014 |
| GSE35957 | Down | -0.2624123300 |
| GSE36640 | Up | 0.1777519974 |
| GSE54402 | Up | 0.1179612808 |
| GSE9593 | Up | 0.0636869995 |
| GSE43922 | Up | 0.6362951140 |
| GSE24585 | Up | 0.1986203176 |
| GSE37065 | Up | 0.1710901261 |
| GSE28863_A1 | Up | 0.1096343249 |
| GSE28863_A2 | Up | 0.0134701292 |
| GSE28863_A3 | Down | -0.7425491521 |
| GSE28863_A4 | Down | -0.0775673047 |
| GSE48662 | Down | -0.2011586278 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027676 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 7513908 | Changes in ABH antigen expression on red cells during in vivo aging: a flow cytometric analysis |
| 7513908 | STUDY DESIGN AND METHODS: Age-dependent changes in the expression of ABH major blood group antigens on red cells were studied in a two-variable flow cytometric analysis |
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