HCSGD entry for GGH
1. General information
| Official gene symbol | GGH |
|---|---|
| Entrez ID | 8836 |
| Gene full name | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| Other gene symbols | GH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006541 | Glutamine metabolic process | IEA | biological_process |
| GO:0008238 | Exopeptidase activity | TAS | molecular_function |
| GO:0008242 | Omega peptidase activity | TAS | molecular_function |
| GO:0010043 | Response to zinc ion | IEA | biological_process |
| GO:0032868 | Response to insulin | IEA | biological_process |
| GO:0034722 | Gamma-glutamyl-peptidase activity | IDA | molecular_function |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0045471 | Response to ethanol | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6610083659 | 0.0012122526 | 0.9999902473 | 0.0661985477 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0241944032 |
| GSE13712_SHEAR | Up | 1.0769205546 |
| GSE13712_STATIC | Up | 0.1441842087 |
| GSE19018 | Up | 1.7071055500 |
| GSE19899_A1 | Down | -1.4482836275 |
| GSE19899_A2 | Down | -0.7035221828 |
| PubMed_21979375_A1 | Down | -0.6446382204 |
| PubMed_21979375_A2 | Down | -0.5911645596 |
| GSE35957 | Down | -1.9086536654 |
| GSE36640 | Down | -2.4065027256 |
| GSE54402 | Down | -0.5004364380 |
| GSE9593 | Down | -0.8932420024 |
| GSE43922 | Up | 0.0199216656 |
| GSE24585 | Down | -0.3836274875 |
| GSE37065 | Down | -0.2329573776 |
| GSE28863_A1 | Down | -0.1445193730 |
| GSE28863_A2 | Up | 0.1078488364 |
| GSE28863_A3 | Down | -0.8949004389 |
| GSE28863_A4 | Up | 0.3202959472 |
| GSE48662 | Down | -1.1412624589 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029881 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
