HCSGD entry for GMPS
1. General information
| Official gene symbol | GMPS |
|---|---|
| Entrez ID | 8833 |
| Gene full name | guanine monphosphate synthetase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003921 | GMP synthase activity | TAS | molecular_function |
| GO:0003922 | GMP synthase (glutamine-hydrolyzing) activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006144 | Purine nucleobase metabolic process | TAS | biological_process |
| GO:0006177 | GMP biosynthetic process | IEA | biological_process |
| GO:0006541 | Glutamine metabolic process | IEA | biological_process |
| GO:0009113 | Purine nucleobase biosynthetic process | TAS | biological_process |
| GO:0009168 | Purine ribonucleoside monophosphate biosynthetic process | TAS | biological_process |
| GO:0016462 | Pyrophosphatase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9678034991 | 0.0073373694 | 0.9999902473 | 0.1713393268 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1398420472 |
| GSE13712_SHEAR | Down | -0.3113996361 |
| GSE13712_STATIC | Down | -0.1056381200 |
| GSE19018 | Down | -0.5491822934 |
| GSE19899_A1 | Down | -0.3800092154 |
| GSE19899_A2 | Down | -1.2695505151 |
| PubMed_21979375_A1 | Down | -1.3734197041 |
| PubMed_21979375_A2 | Down | -1.2048481828 |
| GSE35957 | Down | -0.0874491237 |
| GSE36640 | Down | -1.2758307161 |
| GSE54402 | Down | -0.0455899591 |
| GSE9593 | Down | -0.1415012880 |
| GSE43922 | Down | -0.2631072846 |
| GSE24585 | Down | -0.0162695504 |
| GSE37065 | Down | -0.0870084016 |
| GSE28863_A1 | Up | 0.5347114914 |
| GSE28863_A2 | Up | 0.6223867902 |
| GSE28863_A3 | Down | -0.0871306934 |
| GSE28863_A4 | Down | -0.3749941614 |
| GSE48662 | Down | -0.5236142309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020772 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040905 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050438 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051523 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
