HCSGD entry for CCBL1

1. General information

Official gene symbolCCBL1
Entrez ID883
Gene full namecysteine conjugate-beta lyase, cytoplasmic
Other gene symbolsGTK KAT1 KATI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006559L-phenylalanine catabolic processTASbiological_process
GO:0006569Tryptophan catabolic processTASbiological_process
GO:0006575Cellular modified amino acid metabolic processTASbiological_process
GO:0008483Transaminase activityIEA TASmolecular_function
GO:0008652Cellular amino acid biosynthetic processTASbiological_process
GO:0009058Biosynthetic processIEAbiological_process
GO:0016212Kynurenine-oxoglutarate transaminase activityEXP IDAmolecular_function
GO:0016829Lyase activityIEAmolecular_function
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0036141L-phenylalanine-oxaloacetate transaminase activityTASmolecular_function
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047312L-phenylalanine:pyruvate aminotransferase activityEXPmolecular_function
GO:0047316Glutamine-phenylpyruvate transaminase activityIEAmolecular_function
GO:0047804Cysteine-S-conjugate beta-lyase activityIEAmolecular_function
GO:0047945L-glutamine:pyruvate aminotransferase activityEXPmolecular_function
GO:0070189Kynurenine metabolic processIDAbiological_process
GO:0097053L-kynurenine catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82276720490.81276536610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0133294431
GSE13712_SHEARDown-0.1494002270
GSE13712_STATICDown-0.0213702058
GSE19018Up0.0788906000
GSE19899_A1Down-0.0070640083
GSE19899_A2Down-0.1124507634
PubMed_21979375_A1Down-0.0391817882
PubMed_21979375_A2Down-0.0316200390
GSE35957Down-0.0084639247
GSE36640Down-0.0828232185
GSE54402Up0.1062469981
GSE9593Down-0.0388556305
GSE43922Down-0.0173039991
GSE24585Down-0.0388252822
GSE37065Down-0.0042853366
GSE28863_A1Up0.0947415849
GSE28863_A2Up0.2095653202
GSE28863_A3Down-0.0071048552
GSE28863_A4Up0.1285034603
GSE48662Up0.0329901068

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Pyridoxamine-5'-PhosphateDB02142 EXPT02621
D-PhenylalanineDB02556 EXPT01257
N'-Pyridoxyl-Lysine-5'-MonophosphateDB04083 EXPT02040
1H-INDOL-3-YLACETIC ACIDDB07950 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT041469CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.