HCSGD entry for DPM2
1. General information
| Official gene symbol | DPM2 |
|---|---|
| Entrez ID | 8818 |
| Gene full name | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| Other gene symbols | CDG1U |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000506 | Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex | IDA TAS | cellular_component |
| GO:0004582 | Dolichyl-phosphate beta-D-mannosyltransferase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | TAS | biological_process |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006506 | GPI anchor biosynthetic process | IDA | biological_process |
| GO:0009059 | Macromolecule biosynthetic process | IEA | biological_process |
| GO:0016254 | Preassembly of GPI anchor in ER membrane | TAS | biological_process |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0019348 | Dolichol metabolic process | IEA | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0030234 | Enzyme regulator activity | IEA | molecular_function |
| GO:0031647 | Regulation of protein stability | IPI | biological_process |
| GO:0033185 | Dolichol-phosphate-mannose synthase complex | IDA | cellular_component |
| GO:0035269 | Protein O-linked mannosylation | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2698883857 | 0.5269561415 | 0.9670577844 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2538139182 |
| GSE13712_SHEAR | Down | -0.2205712668 |
| GSE13712_STATIC | Down | -0.2146800766 |
| GSE19018 | Up | 0.0147250091 |
| GSE19899_A1 | Down | -0.2470152791 |
| GSE19899_A2 | Down | -0.0908117112 |
| PubMed_21979375_A1 | Up | 1.3328098272 |
| PubMed_21979375_A2 | Up | 0.4838120126 |
| GSE35957 | Down | -0.1498017702 |
| GSE36640 | Down | -0.0336510644 |
| GSE54402 | Up | 0.3494558695 |
| GSE9593 | Up | 0.0946244192 |
| GSE43922 | Up | 0.3307931612 |
| GSE24585 | Down | -0.3077689656 |
| GSE37065 | Up | 0.1177777582 |
| GSE28863_A1 | Down | -0.1336400226 |
| GSE28863_A2 | Down | -0.0309199384 |
| GSE28863_A3 | Down | -0.0812661621 |
| GSE28863_A4 | Up | 0.0095587458 |
| GSE48662 | Down | -0.1629572439 |

