HCSGD entry for TRIM24

1. General information

Official gene symbolTRIM24
Entrez ID8805
Gene full nametripartite motif containing 24
Other gene symbolsPTC6 RNF82 TF1A TIF1 TIF1A TIF1ALPHA hTIF1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002039P53 bindingIPImolecular_function
GO:0003682Chromatin bindingIDAmolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005102Receptor bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005719Nuclear euchromatinIEAcellular_component
GO:0005726Perichromatin fibrilsIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0016922Ligand-dependent nuclear receptor bindingIEAmolecular_function
GO:0030163Protein catabolic processIMPbiological_process
GO:0031647Regulation of protein stabilityIMPbiological_process
GO:0034056Estrogen response element bindingIDAmolecular_function
GO:0035064Methylated histone residue bindingIDAmolecular_function
GO:0042981Regulation of apoptotic processIMPbiological_process
GO:0043434Response to peptide hormoneIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0046777Protein autophosphorylationIEAbiological_process
GO:0055074Calcium ion homeostasisIEAbiological_process
GO:0070562Regulation of vitamin D receptor signaling pathwayIEAbiological_process
GO:0070577Histone acetyl-lysine bindingIDAmolecular_function
GO:0071391Cellular response to estrogen stimulusIDAbiological_process
GO:1901796Regulation of signal transduction by p53 class mediatorIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77300882570.29118104560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2062762322
GSE13712_SHEARDown-0.2727087430
GSE13712_STATICDown-0.2080425163
GSE19018Down-0.1198868340
GSE19899_A1Up0.1780576025
GSE19899_A2Up0.0185285249
PubMed_21979375_A1Up0.2995194590
PubMed_21979375_A2Down-0.0446585560
GSE35957Down-0.3273782188
GSE36640Down-0.3426196486
GSE54402Up0.1472483990
GSE9593Down-0.1641636842
GSE43922Up0.0071743288
GSE24585Up0.4051016109
GSE37065Down-0.0399758470
GSE28863_A1Down-0.2333736216
GSE28863_A2Up0.1116109186
GSE28863_A3Up0.1482773688
GSE28863_A4Down-0.1623182127
GSE48662Down-0.4775580857

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020969ProteomicsFunctional MTI (Weak)20584899
hsa-miR-1MIMAT0000416MIRT024015ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032466ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032466CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.