HCSGD entry for MPDZ
1. General information
| Official gene symbol | MPDZ |
|---|---|
| Entrez ID | 8777 |
| Gene full name | multiple PDZ domain protein |
| Other gene symbols | HYC2 MUPP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016327 | Apicolateral plasma membrane | IDA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0042552 | Myelination | IEA | biological_process |
| GO:0043220 | Schmidt-Lanterman incisure | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3847875271 | 0.0357894457 | 0.9999902473 | 0.3575484653 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5421416838 |
| GSE13712_SHEAR | Up | 0.1104709821 |
| GSE13712_STATIC | Down | -0.1159196556 |
| GSE19018 | Down | -0.1221836372 |
| GSE19899_A1 | Down | -0.3964053886 |
| GSE19899_A2 | Down | -0.8691073940 |
| PubMed_21979375_A1 | Down | -1.2313854246 |
| PubMed_21979375_A2 | Down | -0.4410576758 |
| GSE35957 | Up | 0.3341616008 |
| GSE36640 | Down | -0.0036116622 |
| GSE54402 | Down | -0.4436418515 |
| GSE9593 | Down | -0.1120006720 |
| GSE43922 | Down | -0.6645646600 |
| GSE24585 | Up | 0.2721562989 |
| GSE37065 | Down | -0.1128362514 |
| GSE28863_A1 | Up | 1.2318376690 |
| GSE28863_A2 | Up | 0.4936221169 |
| GSE28863_A3 | Up | 0.0851686848 |
| GSE28863_A4 | Up | 0.0598599560 |
| GSE48662 | Up | 0.0345169578 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018749 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030077 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
