HCSGD entry for ADAM15
1. General information
| Official gene symbol | ADAM15 |
|---|---|
| Entrez ID | 8751 |
| Gene full name | ADAM metallopeptidase domain 15 |
| Other gene symbols | MDC15 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001669 | Acrosomal vesicle | IEA | cellular_component |
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005912 | Adherens junction | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007160 | Cell-matrix adhesion | TAS | biological_process |
| GO:0008237 | Metallopeptidase activity | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017124 | SH3 domain binding | IPI | molecular_function |
| GO:0030574 | Collagen catabolic process | IEA | biological_process |
| GO:0042246 | Tissue regeneration | IEA | biological_process |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0060317 | Cardiac epithelial to mesenchymal transition | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2184986133 | 0.4124662741 | 0.8991716698 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0712636799 |
| GSE13712_SHEAR | Down | -0.7525453357 |
| GSE13712_STATIC | Up | 0.1185653073 |
| GSE19018 | Up | 0.1135818197 |
| GSE19899_A1 | Down | -0.2318207041 |
| GSE19899_A2 | Up | 0.1824312044 |
| PubMed_21979375_A1 | Up | 0.0735550459 |
| PubMed_21979375_A2 | Up | 0.1597555381 |
| GSE35957 | Down | -0.3719420860 |
| GSE36640 | Up | 0.1741302633 |
| GSE54402 | Down | -0.0764310605 |
| GSE9593 | Up | 0.4086570147 |
| GSE43922 | Up | 0.0354270013 |
| GSE24585 | Down | -0.4726918322 |
| GSE37065 | Up | 0.0762701709 |
| GSE28863_A1 | Up | 0.0943518896 |
| GSE28863_A2 | Up | 0.1839904758 |
| GSE28863_A3 | Up | 0.0068369264 |
| GSE28863_A4 | Down | -0.0033830791 |
| GSE48662 | Up | 1.3759792248 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022149 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
