HCSGD entry for ADAM21
1. General information
| Official gene symbol | ADAM21 |
|---|---|
| Entrez ID | 8747 |
| Gene full name | ADAM metallopeptidase domain 21 |
| Other gene symbols | ADAM 21 ADAM31 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | TAS | biological_process |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032504 | Multicellular organism reproduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2523976635 | 0.9148275521 | 0.9423204113 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3030215075 |
| GSE13712_SHEAR | Down | -0.0268719878 |
| GSE13712_STATIC | Up | 0.0535766070 |
| GSE19018 | Down | -0.0498026650 |
| GSE19899_A1 | Up | 0.2278440072 |
| GSE19899_A2 | Up | 0.0996391814 |
| PubMed_21979375_A1 | Up | 0.3550345173 |
| PubMed_21979375_A2 | Up | 0.2228360002 |
| GSE35957 | Up | 0.0069400515 |
| GSE36640 | Up | 0.1087926807 |
| GSE54402 | Down | -0.2283150859 |
| GSE9593 | Up | 0.0918118998 |
| GSE43922 | Up | 0.6524538159 |
| GSE24585 | Down | -0.0280104975 |
| GSE37065 | Down | -0.0919685197 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0616822197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016846 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
