HCSGD entry for TNFSF9


1. General information

Official gene symbolTNFSF9
Entrez ID8744
Gene full nametumor necrosis factor (ligand) superfamily, member 9
Other gene symbols4-1BB-L CD137L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingTASmolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005164Tumor necrosis factor receptor bindingIEAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0032729Positive regulation of interferon-gamma productionIEAbiological_process
GO:0032735Positive regulation of interleukin-12 productionIEAbiological_process
GO:0032755Positive regulation of interleukin-6 productionIEAbiological_process
GO:0042104Positive regulation of activated T cell proliferationIEAbiological_process
GO:0043011Myeloid dendritic cell differentiationIEAbiological_process
GO:0045585Positive regulation of cytotoxic T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00490822540.99067043050.18365582391.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6781529167
GSE13712_SHEARDown-0.2350737987
GSE13712_STATICUp0.4339188650
GSE19018Up0.1719066106
GSE19899_A1Up0.0641343281
GSE19899_A2Up0.7498629350
PubMed_21979375_A1Up0.7746069061
PubMed_21979375_A2Up0.6162590025
GSE35957Up0.0641701926
GSE36640Up1.4209163861
GSE54402Up0.9514705189
GSE9593Up0.3784195828
GSE43922Up0.0642828990
GSE24585Up0.3522554519
GSE37065Up0.4252604925
GSE28863_A1Down-0.0395741331
GSE28863_A2Up0.0668801697
GSE28863_A3Up0.2124763272
GSE28863_A4Up0.1390512937
GSE48662Up0.1498334597

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001405pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-335-5pMIMAT0000765MIRT017011MicroarrayFunctional MTI (Weak)18185580
hsa-miR-98-5pMIMAT0000096MIRT027516MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT028983MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.