HCSGD entry for TNFSF9
1. General information
| Official gene symbol | TNFSF9 |
|---|---|
| Entrez ID | 8744 |
| Gene full name | tumor necrosis factor (ligand) superfamily, member 9 |
| Other gene symbols | 4-1BB-L CD137L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032729 | Positive regulation of interferon-gamma production | IEA | biological_process |
| GO:0032735 | Positive regulation of interleukin-12 production | IEA | biological_process |
| GO:0032755 | Positive regulation of interleukin-6 production | IEA | biological_process |
| GO:0042104 | Positive regulation of activated T cell proliferation | IEA | biological_process |
| GO:0043011 | Myeloid dendritic cell differentiation | IEA | biological_process |
| GO:0045585 | Positive regulation of cytotoxic T cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0049082254 | 0.9906704305 | 0.1836558239 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6781529167 |
| GSE13712_SHEAR | Down | -0.2350737987 |
| GSE13712_STATIC | Up | 0.4339188650 |
| GSE19018 | Up | 0.1719066106 |
| GSE19899_A1 | Up | 0.0641343281 |
| GSE19899_A2 | Up | 0.7498629350 |
| PubMed_21979375_A1 | Up | 0.7746069061 |
| PubMed_21979375_A2 | Up | 0.6162590025 |
| GSE35957 | Up | 0.0641701926 |
| GSE36640 | Up | 1.4209163861 |
| GSE54402 | Up | 0.9514705189 |
| GSE9593 | Up | 0.3784195828 |
| GSE43922 | Up | 0.0642828990 |
| GSE24585 | Up | 0.3522554519 |
| GSE37065 | Up | 0.4252604925 |
| GSE28863_A1 | Down | -0.0395741331 |
| GSE28863_A2 | Up | 0.0668801697 |
| GSE28863_A3 | Up | 0.2124763272 |
| GSE28863_A4 | Up | 0.1390512937 |
| GSE48662 | Up | 0.1498334597 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001405 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017011 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027516 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028983 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
