HCSGD entry for GPAA1
1. General information
| Official gene symbol | GPAA1 |
|---|---|
| Entrez ID | 8733 |
| Gene full name | glycosylphosphatidylinositol anchor attachment 1 |
| Other gene symbols | GAA1 hGAA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003923 | GPI-anchor transamidase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006461 | Protein complex assembly | NAS | biological_process |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006621 | Protein retention in ER lumen | NAS | biological_process |
| GO:0015631 | Tubulin binding | NAS | molecular_function |
| GO:0016255 | Attachment of GPI anchor to protein | NAS TAS | biological_process |
| GO:0034235 | GPI anchor binding | IMP | molecular_function |
| GO:0042765 | GPI-anchor transamidase complex | IEA TAS | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7775335056 | 0.0502606664 | 0.9999902473 | 0.4201051127 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2303243381 |
| GSE13712_SHEAR | Down | -0.4812896517 |
| GSE13712_STATIC | Down | -0.6381939628 |
| GSE19018 | Up | 0.2182697347 |
| GSE19899_A1 | Down | -0.8495510296 |
| GSE19899_A2 | Down | -0.3688784962 |
| PubMed_21979375_A1 | Up | 0.5799265534 |
| PubMed_21979375_A2 | Up | 0.1830536616 |
| GSE35957 | Down | -0.1222304106 |
| GSE36640 | Up | 0.4201199158 |
| GSE54402 | Up | 0.0271255737 |
| GSE9593 | Up | 0.0357953908 |
| GSE43922 | Down | -0.3373230884 |
| GSE24585 | Up | 0.1189339872 |
| GSE37065 | Down | -0.5684316380 |
| GSE28863_A1 | Down | -0.2783469811 |
| GSE28863_A2 | Down | -0.2569774328 |
| GSE28863_A3 | Down | -0.1778016926 |
| GSE28863_A4 | Down | -0.2898743022 |
| GSE48662 | Up | 0.4551175552 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023933 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025943 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051180 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
