HCSGD entry for RNGTT


1. General information

Official gene symbolRNGTT
Entrez ID8732
Gene full nameRNA guanylyltransferase and 5'-phosphatase
Other gene symbolsCAP1A HCE HCE1 hCAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004484MRNA guanylyltransferase activityIEAmolecular_function
GO:0004651Polynucleotide 5'-phosphatase activityIEAmolecular_function
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005634NucleusIEA TAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingIEA TASbiological_process
GO:0006396RNA processingTASbiological_process
GO:0008138Protein tyrosine/serine/threonine phosphatase activityIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61885816270.71425448120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0640790435
GSE13712_SHEARUp0.0765721016
GSE13712_STATICUp0.1461893895
GSE19018Down-0.1022417818
GSE19899_A1Up0.0285286626
GSE19899_A2Down-0.0367799159
PubMed_21979375_A1Up0.3985617694
PubMed_21979375_A2Up0.1112226143
GSE35957Down-0.0013341344
GSE36640Down-0.3172539000
GSE54402Up0.2138032967
GSE9593Down-0.0969330517
GSE43922Up0.0067867182
GSE24585Up0.2683940223
GSE37065Up0.0415848407
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2571127353

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Isopropyl AlcoholDB02325 EXPT01912 | DB04402

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-25-3pMIMAT0000081MIRT050338CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050539CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.