HCSGD entry for URI1
1. General information
| Official gene symbol | URI1 |
|---|---|
| Entrez ID | 8725 |
| Gene full name | URI1, prefoldin-like chaperone |
| Other gene symbols | C19orf2 NNX3 PPP1R19 RMP URI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0001106 | RNA polymerase II transcription corepressor activity | IDA IMP | molecular_function |
| GO:0001558 | Regulation of cell growth | IDA | biological_process |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0004864 | Protein phosphatase inhibitor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005665 | DNA-directed RNA polymerase II, core complex | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA IMP | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0009615 | Response to virus | IMP | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IMP | biological_process |
| GO:0016272 | Prefoldin complex | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0071363 | Cellular response to growth factor stimulus | IDA | biological_process |
| GO:0071383 | Cellular response to steroid hormone stimulus | IDA | biological_process |
| GO:2001243 | Negative regulation of intrinsic apoptotic signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8810868470 | 0.1484000114 | 0.9999902473 | 0.7452846213 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1146113190 |
| GSE13712_SHEAR | Down | -0.0489821497 |
| GSE13712_STATIC | Down | -0.0037472014 |
| GSE19018 | Up | 0.1602424007 |
| GSE19899_A1 | Down | -0.2667712478 |
| GSE19899_A2 | Down | -0.0238407778 |
| PubMed_21979375_A1 | Up | 0.2297178355 |
| PubMed_21979375_A2 | Down | -0.3569281039 |
| GSE35957 | Up | 0.0926472320 |
| GSE36640 | Down | -0.4335397780 |
| GSE54402 | Up | 0.0096552071 |
| GSE9593 | Up | 0.1123664308 |
| GSE43922 | Down | -0.0990800231 |
| GSE24585 | Down | -0.2093619687 |
| GSE37065 | Down | -0.2825690086 |
| GSE28863_A1 | Up | 0.0809574391 |
| GSE28863_A2 | Up | 0.0314895843 |
| GSE28863_A3 | Down | -0.5718085785 |
| GSE28863_A4 | Up | 0.3669138577 |
| GSE48662 | Down | -0.5650667503 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-598-3p | MIMAT0003266 | MIRT040496 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
