HCSGD entry for EDF1
1. General information
| Official gene symbol | EDF1 |
|---|---|
| Entrez ID | 8721 |
| Gene full name | endothelial differentiation-related factor 1 |
| Other gene symbols | EDF-1 MBF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IMP | molecular_function |
| GO:0003713 | Transcription coactivator activity | IMP | molecular_function |
| GO:0004402 | Histone acetyltransferase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005622 | Intracellular | TAS | cellular_component |
| GO:0005634 | Nucleus | IDA IMP NAS | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IMP | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | IDA | molecular_function |
| GO:0019216 | Regulation of lipid metabolic process | TAS | biological_process |
| GO:0043388 | Positive regulation of DNA binding | IDA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045446 | Endothelial cell differentiation | TAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6787980662 | 0.4065772729 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2211526977 |
| GSE13712_SHEAR | Down | -0.1618630842 |
| GSE13712_STATIC | Down | -0.0561518601 |
| GSE19018 | Up | 0.2175818995 |
| GSE19899_A1 | Up | 0.0765526469 |
| GSE19899_A2 | Up | 0.0549742065 |
| PubMed_21979375_A1 | Up | 0.3610930107 |
| PubMed_21979375_A2 | Down | -0.1751037696 |
| GSE35957 | Down | -0.2840805278 |
| GSE36640 | Up | 0.2643575481 |
| GSE54402 | Up | 0.3573094713 |
| GSE9593 | Up | 0.0384842731 |
| GSE43922 | Down | -0.0380317235 |
| GSE24585 | Down | -0.0043832499 |
| GSE37065 | Down | -0.0973665746 |
| GSE28863_A1 | Down | -0.3942448783 |
| GSE28863_A2 | Down | -0.5418308798 |
| GSE28863_A3 | Up | 0.0391632630 |
| GSE28863_A4 | Up | 0.0784220938 |
| GSE48662 | Up | 0.0649526778 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023925 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038500 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039892 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040630 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040953 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044209 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045491 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
