HCSGD entry for ABCC3
1. General information
| Official gene symbol | ABCC3 |
|---|---|
| Entrez ID | 8714 |
| Gene full name | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| Other gene symbols | ABC31 EST90757 MLP2 MOAT-D MRP3 cMOAT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0008514 | Organic anion transmembrane transporter activity | TAS | molecular_function |
| GO:0015721 | Bile acid and bile salt transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4077806162 | 0.2572574370 | 0.9999902473 | 0.9723252441 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1952591891 |
| GSE13712_SHEAR | Up | 0.3915982483 |
| GSE13712_STATIC | Up | 0.1290940597 |
| GSE19018 | Down | -0.1718897046 |
| GSE19899_A1 | Down | -0.0797657853 |
| GSE19899_A2 | Down | -0.1726042776 |
| PubMed_21979375_A1 | Down | -0.3575910010 |
| PubMed_21979375_A2 | Down | -0.1504267565 |
| GSE35957 | Up | 0.4100073027 |
| GSE36640 | Up | 0.1746531237 |
| GSE54402 | Up | 0.0883547636 |
| GSE9593 | Up | 0.0424018275 |
| GSE43922 | Down | -0.1458706347 |
| GSE24585 | Up | 0.0630747702 |
| GSE37065 | Down | -0.3034402024 |
| GSE28863_A1 | Up | 0.5900043624 |
| GSE28863_A2 | Up | 0.3013517260 |
| GSE28863_A3 | Down | -0.0619425299 |
| GSE28863_A4 | Down | -0.2135134331 |
| GSE48662 | Up | 0.1227730908 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT003824 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT004155 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017472 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022500 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20937408 | One of these differentially expressed proteins was found to be the multidrug resistance-associated protein (MGr1-Ag) |
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