HCSGD entry for B4GALT2
1. General information
| Official gene symbol | B4GALT2 |
|---|---|
| Entrez ID | 8704 |
| Gene full name | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| Other gene symbols | B4Gal-T2 B4Gal-T3 beta4Gal-T2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0003831 | Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity | IEA | molecular_function |
| GO:0003945 | N-acetyllactosamine synthase activity | IEA | molecular_function |
| GO:0004461 | Lactose synthase activity | IEA | molecular_function |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0008378 | Galactosyltransferase activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018146 | Keratan sulfate biosynthetic process | TAS | biological_process |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0032580 | Golgi cisterna membrane | IEA | cellular_component |
| GO:0042339 | Keratan sulfate metabolic process | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9877414080 | 0.0068830440 | 0.9999902473 | 0.1653088342 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0951399437 |
| GSE13712_SHEAR | Up | 0.1146521164 |
| GSE13712_STATIC | Up | 0.0111787928 |
| GSE19018 | Down | -0.0748980286 |
| GSE19899_A1 | Down | -0.6663577481 |
| GSE19899_A2 | Down | -0.2692701339 |
| PubMed_21979375_A1 | Down | -1.0810036072 |
| PubMed_21979375_A2 | Down | -0.6585533176 |
| GSE35957 | Down | -0.3282448489 |
| GSE36640 | Up | 0.0671877327 |
| GSE54402 | Down | -0.3120447459 |
| GSE9593 | Up | 0.0845447250 |
| GSE43922 | Down | -0.3349421957 |
| GSE24585 | Down | -0.9732618039 |
| GSE37065 | Down | -0.3982824662 |
| GSE28863_A1 | Down | -0.4766523142 |
| GSE28863_A2 | Down | -0.0278528348 |
| GSE28863_A3 | Down | -0.4434809305 |
| GSE28863_A4 | Down | -0.2275340044 |
| GSE48662 | Up | 0.4006644467 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-Acetyl-D-glucosamine | DB00141 | NUTR00040 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT046876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049075 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050596 | CLASH | Functional MTI (Weak) | 23622248 |
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