HCSGD entry for CDC23

1. General information

Official gene symbolCDC23
Entrez ID8697
Gene full namecell division cycle 23
Other gene symbolsANAPC8 APC8 CUT23
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000080Mitotic G1 phaseIDAbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0004842Ubiquitin-protein ligase activityTASmolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processTASbiological_process
GO:0007049Cell cycleTASbiological_process
GO:0007067MitosisIDAbiological_process
GO:0007080Mitotic metaphase plate congressionIDAbiological_process
GO:0007091Metaphase/anaphase transition of mitotic cell cycleTASbiological_process
GO:0007094Mitotic spindle assembly checkpointTASbiological_process
GO:0007096Regulation of exit from mitosisTASbiological_process
GO:0030071Regulation of mitotic metaphase/anaphase transitionIDA IEAbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070979Protein K11-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91818552870.03148554010.99999024730.3330202410

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1576421579
GSE13712_SHEARUp0.7753327206
GSE13712_STATICUp0.3057529301
GSE19018Down-0.2540071643
GSE19899_A1Down-0.3219602042
GSE19899_A2Down-0.3735688586
PubMed_21979375_A1Up0.0920058259
PubMed_21979375_A2Down-0.8010105917
GSE35957Down-0.0050253216
GSE36640Down-0.5642573608
GSE54402Down-0.0765742339
GSE9593Down-0.4142176940
GSE43922Down-0.3057763323
GSE24585Up0.2502302982
GSE37065Down-0.2214796769
GSE28863_A1Down-0.1348189788
GSE28863_A2Up0.1663190532
GSE28863_A3Down-0.7228458052
GSE28863_A4Down-0.1575988571
GSE48662Down-0.2451962974

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019590SequencingFunctional MTI (Weak)20371350
hsa-miR-29c-3pMIMAT0000681MIRT020394SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025367ProteomicsFunctional MTI (Weak)21566225
hsa-miR-98-5pMIMAT0000096MIRT027586MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031557ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.