HCSGD entry for MARCO

1. General information

Official gene symbolMARCO
Entrez ID8685
Gene full namemacrophage receptor with collagenous structure
Other gene symbolsSCARA2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002221Pattern recognition receptor signaling pathwayTASbiological_process
GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005581CollagenIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0008329Signaling pattern recognition receptor activityTASmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0043277Apoptotic cell clearanceIEAbiological_process
GO:0045087Innate immune responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75444578470.62455569700.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0901290446
GSE13712_SHEARDown-0.1450714414
GSE13712_STATICDown-0.0184533590
GSE19018Up0.0828351316
GSE19899_A1Up0.1046872458
GSE19899_A2Up0.2365572807
PubMed_21979375_A1Down-0.4884318117
PubMed_21979375_A2Down-0.1664537392
GSE35957Down-0.0863672393
GSE36640Up0.0939725078
GSE54402Down-0.1396293829
GSE9593Down-0.0001992542
GSE43922Up0.0389004234
GSE24585Down-0.0858920161
GSE37065Up0.0698039898
GSE28863_A1Down-0.0198207182
GSE28863_A2Up0.0030859763
GSE28863_A3Up0.2759701690
GSE28863_A4Up0.1008990464
GSE48662Up0.0333861341

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.