HCSGD entry for EIF3I
1. General information
| Official gene symbol | EIF3I |
|---|---|
| Entrez ID | 8668 |
| Gene full name | eukaryotic translation initiation factor 3, subunit I |
| Other gene symbols | EIF3S2 PRO2242 TRIP-1 TRIP1 eIF3-beta eIF3-p36 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC IDA IEA TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5163824019 | 0.3730123362 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4936712803 |
| GSE13712_SHEAR | Up | 0.0677710011 |
| GSE13712_STATIC | Up | 0.1258268884 |
| GSE19018 | Down | -0.2102928635 |
| GSE19899_A1 | Up | 0.1808098449 |
| GSE19899_A2 | Up | 0.0497022460 |
| PubMed_21979375_A1 | Up | 0.2499609626 |
| PubMed_21979375_A2 | Up | 0.0021567872 |
| GSE35957 | Down | -0.3740944879 |
| GSE36640 | Down | -0.2577367497 |
| GSE54402 | Up | 0.4853429327 |
| GSE9593 | Down | -0.0354737769 |
| GSE43922 | Up | 0.0678248422 |
| GSE24585 | Down | -0.3668178091 |
| GSE37065 | Down | -0.0081789326 |
| GSE28863_A1 | Up | 0.0679893375 |
| GSE28863_A2 | Up | 0.0175801342 |
| GSE28863_A3 | Down | -0.4513173787 |
| GSE28863_A4 | Down | -0.2332033725 |
| GSE48662 | Down | -0.3644116080 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016316 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016316 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1303 | MIMAT0005891 | MIRT035890 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-532-3p | MIMAT0004780 | MIRT037924 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040929 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045793 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046640 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049001 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
