HCSGD entry for EIF3G
1. General information
| Official gene symbol | EIF3G |
|---|---|
| Entrez ID | 8666 |
| Gene full name | eukaryotic translation initiation factor 3, subunit G |
| Other gene symbols | EIF3-P42 EIF3S4 eIF3-delta eIF3-p44 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC IDA TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7008872307 | 0.1880924433 | 0.9999902473 | 0.8403974198 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4908115504 |
| GSE13712_SHEAR | Down | -0.1912428082 |
| GSE13712_STATIC | Down | -0.0550219082 |
| GSE19018 | Down | -0.3231888162 |
| GSE19899_A1 | Down | -0.4971113269 |
| GSE19899_A2 | Up | 0.2217167891 |
| PubMed_21979375_A1 | Up | 0.9677403999 |
| PubMed_21979375_A2 | Down | -0.0844989243 |
| GSE35957 | Down | -0.3541664643 |
| GSE36640 | Down | -0.0399511114 |
| GSE54402 | Up | 0.1947021331 |
| GSE9593 | Down | -0.0819530272 |
| GSE43922 | Down | -0.2072625080 |
| GSE24585 | Down | -0.2139977853 |
| GSE37065 | Down | -0.2791098425 |
| GSE28863_A1 | Up | 0.0237066966 |
| GSE28863_A2 | Down | -0.2679577729 |
| GSE28863_A3 | Down | -0.0305163432 |
| GSE28863_A4 | Up | 0.0964898329 |
| GSE48662 | Up | 0.1817736536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020496 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039322 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045194 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049415 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
