HCSGD entry for EIF3F
1. General information
| Official gene symbol | EIF3F |
|---|---|
| Entrez ID | 8665 |
| Gene full name | eukaryotic translation initiation factor 3, subunit F |
| Other gene symbols | EIF3S5 eIF3-p47 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IDA IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC IDA TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4803621443 | 0.3185361878 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0093765566 |
| GSE13712_SHEAR | Down | -0.0648358299 |
| GSE13712_STATIC | Down | -0.1928443636 |
| GSE19018 | Up | 0.1206849689 |
| GSE19899_A1 | Down | -0.2680938364 |
| GSE19899_A2 | Up | 0.0401514034 |
| PubMed_21979375_A1 | Down | -0.1543352106 |
| PubMed_21979375_A2 | Down | -0.3070902006 |
| GSE35957 | Up | 0.3922654750 |
| GSE36640 | Down | -0.2900694660 |
| GSE54402 | Down | -0.1879846393 |
| GSE9593 | Up | 0.1842305577 |
| GSE43922 | Down | -0.2968603325 |
| GSE24585 | Up | 0.0165979167 |
| GSE37065 | Down | -0.3988748236 |
| GSE28863_A1 | Up | 0.4309253896 |
| GSE28863_A2 | Up | 0.8891472809 |
| GSE28863_A3 | Up | 0.1544762569 |
| GSE28863_A4 | Down | -0.0069641877 |
| GSE48662 | Up | 0.0668358809 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021009 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032018 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044355 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044466 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
