HCSGD entry for EIF3D
1. General information
| Official gene symbol | EIF3D |
|---|---|
| Entrez ID | 8664 |
| Gene full name | eukaryotic translation initiation factor 3, subunit D |
| Other gene symbols | EIF3S7 eIF3-p66 eIF3-zeta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0001732 | Formation of translation initiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC IDA TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1826438851 | 0.7508159037 | 0.8364597010 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0289744177 |
| GSE13712_SHEAR | Down | -0.3811040513 |
| GSE13712_STATIC | Down | -0.1120799394 |
| GSE19018 | Up | 0.3920437095 |
| GSE19899_A1 | Up | 0.3928532526 |
| GSE19899_A2 | Up | 0.4036812799 |
| PubMed_21979375_A1 | Up | 0.5052681876 |
| PubMed_21979375_A2 | Up | 0.3139821687 |
| GSE35957 | Down | -0.3268752472 |
| GSE36640 | Down | -0.1452567691 |
| GSE54402 | Up | 0.5869808998 |
| GSE9593 | Up | 0.0336691917 |
| GSE43922 | Up | 0.1493279041 |
| GSE24585 | Up | 0.1256923759 |
| GSE37065 | Down | -0.1167423564 |
| GSE28863_A1 | Down | -0.0044811885 |
| GSE28863_A2 | Down | -0.1576997900 |
| GSE28863_A3 | Down | -0.1979886629 |
| GSE28863_A4 | Up | 0.1067792753 |
| GSE48662 | Down | -0.4650823597 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037879 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038210 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040086 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043981 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052211 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
