HCSGD entry for CBFB

1. General information

Official gene symbolCBFB
Entrez ID865
Gene full namecore-binding factor, beta subunit
Other gene symbolsPEBP2B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001649Osteoblast differentiationIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003713Transcription coactivator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005634NucleusIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0030098Lymphocyte differentiationIEAbiological_process
GO:0030099Myeloid cell differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048469Cell maturationIEAbiological_process
GO:0060216Definitive hemopoiesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17756061320.33713786710.82659584371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3062092341
GSE13712_SHEARUp0.3151464133
GSE13712_STATICDown-0.0683082734
GSE19018Down-0.5178360965
GSE19899_A1Up0.3868836136
GSE19899_A2Down-0.1896602721
PubMed_21979375_A1Up0.4592625069
PubMed_21979375_A2Down-0.1980573470
GSE35957Down-0.4648127946
GSE36640Down-0.8102879638
GSE54402Up0.6520281123
GSE9593Down-0.3316137939
GSE43922Up0.2344708701
GSE24585Down-0.2052965673
GSE37065Down-0.0582515956
GSE28863_A1Up0.1295819765
GSE28863_A2Up0.3241942885
GSE28863_A3Down-0.3611758661
GSE28863_A4Up0.3041257860
GSE48662Down-0.1225210205

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT000676qRT-PCR//Luciferase reporter assay//Microarray//Reporter assay;OtherFunctional MTI19915607
hsa-miR-145-5pMIMAT0000437MIRT000676Luciferase reporter assayNon-Functional MTI20737575
hsa-miR-155-5pMIMAT0000646MIRT001562pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-125b-5pMIMAT0000423MIRT003970MicroarrayFunctional MTI (Weak)17891175
hsa-miR-125b-5pMIMAT0000423MIRT003970Luciferase reporter assayFunctional MTI22689670
hsa-let-7b-5pMIMAT0000063MIRT005054MicroarrayFunctional MTI (Weak)17699775
hsa-miR-30a-5pMIMAT0000087MIRT005217pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-130b-3pMIMAT0000691MIRT020330SequencingFunctional MTI (Weak)20371350
hsa-miR-615-3pMIMAT0003283MIRT039772CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049318CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-145-5pMIMAT0000437NAhsa-miR-14519915607
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.