HCSGD entry for LAMTOR3
1. General information
| Official gene symbol | LAMTOR3 |
|---|---|
| Entrez ID | 8649 |
| Gene full name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| Other gene symbols | MAP2K1IP1 MAPBP MAPKSP1 MP1 PRO0633 Ragulator3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0032008 | Positive regulation of TOR signaling | IMP | biological_process |
| GO:0032947 | Protein complex scaffold | IDA | molecular_function |
| GO:0034613 | Cellular protein localization | IMP | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0071230 | Cellular response to amino acid stimulus | IMP | biological_process |
| GO:0071986 | Ragulator complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3615445234 | 0.3127151552 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5222855739 |
| GSE13712_SHEAR | Down | -0.3451590306 |
| GSE13712_STATIC | Down | -0.1369188943 |
| GSE19018 | Down | -0.3910463482 |
| GSE19899_A1 | Up | 0.0579988815 |
| GSE19899_A2 | Up | 0.1179636644 |
| PubMed_21979375_A1 | Up | 0.1674919137 |
| PubMed_21979375_A2 | Up | 0.4397712695 |
| GSE35957 | Up | 0.3011730027 |
| GSE36640 | Up | 0.2107066046 |
| GSE54402 | Up | 0.0469135356 |
| GSE9593 | Up | 0.2319227516 |
| GSE43922 | Up | 0.1775778698 |
| GSE24585 | Up | 0.4325818774 |
| GSE37065 | Up | 0.0586988270 |
| GSE28863_A1 | Down | -0.3768007005 |
| GSE28863_A2 | Down | -0.1187842247 |
| GSE28863_A3 | Down | -0.4440464212 |
| GSE28863_A4 | Down | -0.2678492569 |
| GSE48662 | Down | -0.4612660346 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT005437 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030592 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
