HCSGD entry for OASL
1. General information
| Official gene symbol | OASL |
|---|---|
| Entrez ID | 8638 |
| Gene full name | 2'-5'-oligoadenylate synthetase-like |
| Other gene symbols | OASLd TRIP-14 TRIP14 p59 OASL p59-OASL p59OASL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001730 | 2'-5'-oligoadenylate synthetase activity | IDA | molecular_function |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003725 | Double-stranded RNA binding | IDA IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0009615 | Response to virus | IDA | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
| GO:0046966 | Thyroid hormone receptor binding | TAS | molecular_function |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0049928232 | 0.5635380191 | 0.1853541608 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0512997340 |
| GSE13712_SHEAR | Up | 3.8270291250 |
| GSE13712_STATIC | Up | 2.6859959220 |
| GSE19018 | Up | 0.1577555672 |
| GSE19899_A1 | Up | 0.0576612896 |
| GSE19899_A2 | Up | 0.1766586654 |
| PubMed_21979375_A1 | Down | -0.0002236387 |
| PubMed_21979375_A2 | Down | -0.0261741470 |
| GSE35957 | Down | -4.2523998003 |
| GSE36640 | Up | 0.1604148015 |
| GSE54402 | Up | 0.2014873062 |
| GSE9593 | Up | 0.2630831047 |
| GSE43922 | Up | 0.0146001632 |
| GSE24585 | Up | 0.5938462792 |
| GSE37065 | Up | 1.3200607973 |
| GSE28863_A1 | Up | 0.0461308895 |
| GSE28863_A2 | Up | 1.3647290137 |
| GSE28863_A3 | Up | 0.0717829908 |
| GSE28863_A4 | Down | -0.1211041558 |
| GSE48662 | Up | 0.2673892205 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021250 | Microarray | Functional MTI (Weak) | 18057241 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022684 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023766 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
