HCSGD entry for PPAP2B

1. General information

Official gene symbolPPAP2B
Entrez ID8613
Gene full namephosphatidic acid phosphatase type 2B
Other gene symbolsDri42 LPP3 PAP2B VCIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001568Blood vessel developmentIEAbiological_process
GO:0001702Gastrulation with mouth forming secondIEAbiological_process
GO:0001933Negative regulation of protein phosphorylationIDAbiological_process
GO:0004721Phosphoprotein phosphatase activityTASmolecular_function
GO:0005178Integrin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005912Adherens junctionTAScellular_component
GO:0006629Lipid metabolic processNASbiological_process
GO:0006644Phospholipid metabolic processIEAbiological_process
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0008195Phosphatidate phosphatase activityIEAmolecular_function
GO:0008354Germ cell migrationTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016311DephosphorylationTASbiological_process
GO:0030111Regulation of Wnt signaling pathwayIEAbiological_process
GO:0030148Sphingolipid biosynthetic processTASbiological_process
GO:0034109Homotypic cell-cell adhesionIDAbiological_process
GO:0042577Lipid phosphatase activityIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0044328Canonical Wnt signaling pathway involved in positive regulation of endothelial cell migrationIMPbiological_process
GO:0044329Canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesionIMPbiological_process
GO:0044330Canonical Wnt signaling pathway involved in positive regulation of wound healingIMPbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIEAbiological_process
GO:0050821Protein stabilizationIDAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81580251510.00090646250.99999024730.0567192399

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2397170650
GSE13712_SHEARDown-0.7755255697
GSE13712_STATICDown-0.3908892657
GSE19018Down-0.9727435512
GSE19899_A1Down-2.5211959190
GSE19899_A2Down-1.9149688384
PubMed_21979375_A1Down-1.7561695239
PubMed_21979375_A2Down-2.9707063880
GSE35957Down-0.1460361742
GSE36640Down-0.2622080432
GSE54402Down-0.8075662434
GSE9593Up0.6379258528
GSE43922Down-2.0497863876
GSE24585Down-0.0662451062
GSE37065Down-0.0299036433
GSE28863_A1Up0.4415572984
GSE28863_A2Up0.1343840101
GSE28863_A3Up0.4311657221
GSE28863_A4Down-0.1496372581
GSE48662Down-0.3603311822

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017904MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT022602MicroarrayFunctional MTI (Weak)18668037
hsa-miR-7-5pMIMAT0000252MIRT025737MicroarrayFunctional MTI (Weak)19073608
hsa-miR-98-5pMIMAT0000096MIRT027643MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.