HCSGD entry for PLA2G4C
1. General information
| Official gene symbol | PLA2G4C |
|---|---|
| Entrez ID | 8605 |
| Gene full name | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| Other gene symbols | CPLA2-gamma |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004620 | Phospholipase activity | IEA | molecular_function |
| GO:0005543 | Phospholipid binding | NAS | molecular_function |
| GO:0005635 | Nuclear envelope | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006954 | Inflammatory response | NAS | biological_process |
| GO:0007567 | Parturition | NAS | biological_process |
| GO:0008152 | Metabolic process | IEA | biological_process |
| GO:0009395 | Phospholipid catabolic process | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0019369 | Arachidonic acid metabolic process | NAS | biological_process |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0036149 | Phosphatidylinositol acyl-chain remodeling | TAS | biological_process |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | TAS | biological_process |
| GO:0036152 | Phosphatidylethanolamine acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0046475 | Glycerophospholipid catabolic process | IDA | biological_process |
| GO:0047499 | Calcium-independent phospholipase A2 activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0085718780 | 0.9788398047 | 0.2374343849 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8238638762 |
| GSE13712_SHEAR | Up | 0.5095598016 |
| GSE13712_STATIC | Up | 0.8119809054 |
| GSE19018 | Up | 0.0615915840 |
| GSE19899_A1 | Down | -0.0127806265 |
| GSE19899_A2 | Up | 0.6969046317 |
| PubMed_21979375_A1 | Up | 0.0595438147 |
| PubMed_21979375_A2 | Up | 0.3266589784 |
| GSE35957 | Up | 0.0369204479 |
| GSE36640 | Up | 1.2686785327 |
| GSE54402 | Up | 0.2479679372 |
| GSE9593 | Up | 0.1288726587 |
| GSE43922 | Down | -0.0455013851 |
| GSE24585 | Up | 0.5304416413 |
| GSE37065 | Up | 0.6548527638 |
| GSE28863_A1 | Down | -0.0693338264 |
| GSE28863_A2 | Up | 0.1179988718 |
| GSE28863_A3 | Down | -0.0550859577 |
| GSE28863_A4 | Up | 0.0290960087 |
| GSE48662 | Up | 0.4144618203 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021740 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022128 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025081 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
