HCSGD entry for KHSRP
1. General information
| Official gene symbol | KHSRP |
|---|---|
| Entrez ID | 8570 |
| Gene full name | KH-type splicing regulatory protein |
| Other gene symbols | FBP2 FUBP2 KSRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0010494 | Cytoplasmic stress granule | IEA | cellular_component |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8697316857 | 0.1948500019 | 0.9999902473 | 0.8553733167 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0184687739 |
| GSE13712_SHEAR | Down | -0.1191773171 |
| GSE13712_STATIC | Down | -0.0094850279 |
| GSE19018 | Down | -0.3335457994 |
| GSE19899_A1 | Down | -0.1287344030 |
| GSE19899_A2 | Up | 0.1574779024 |
| PubMed_21979375_A1 | Up | 0.0739925991 |
| PubMed_21979375_A2 | Down | -0.0985841823 |
| GSE35957 | Down | -0.2164004089 |
| GSE36640 | Down | -0.6465305503 |
| GSE54402 | Up | 0.2120936722 |
| GSE9593 | Down | -0.2753584521 |
| GSE43922 | Down | -0.0375937620 |
| GSE24585 | Down | -0.2044708555 |
| GSE37065 | Down | -0.2654984550 |
| GSE28863_A1 | Up | 0.0069244244 |
| GSE28863_A2 | Down | -0.0317475040 |
| GSE28863_A3 | Up | 0.3688556582 |
| GSE28863_A4 | Up | 0.1097639829 |
| GSE48662 | Up | 0.2164911628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT005397 | qRT-PCR | Functional MTI (Weak) | 19296935 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT005397 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT006988 | Western blot, luciferase assay | Functional MTI | 22615562 |
| hsa-miR-590-3p | MIMAT0004801 | MIRT016217 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035948 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-940 | MIMAT0004983 | MIRT036633 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039660 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045215 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045395 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045963 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046948 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049309 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052159 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
