HCSGD entry for CDK10
1. General information
| Official gene symbol | CDK10 |
|---|---|
| Entrez ID | 8558 |
| Gene full name | cyclin-dependent kinase 10 |
| Other gene symbols | PISSLRE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0007049 | Cell cycle | TAS | biological_process |
| GO:0007089 | Traversing start control point of mitotic cell cycle | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9804524904 | 0.0356555716 | 0.9999902473 | 0.3572032675 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1064486181 |
| GSE13712_SHEAR | Down | -0.1341499535 |
| GSE13712_STATIC | Down | -0.3898446729 |
| GSE19018 | Up | 0.0783894786 |
| GSE19899_A1 | Down | -0.2403251893 |
| GSE19899_A2 | Down | -0.4335153401 |
| PubMed_21979375_A1 | Up | 0.3005576936 |
| PubMed_21979375_A2 | Down | -0.8068906051 |
| GSE35957 | Down | -0.3281907828 |
| GSE36640 | Down | -0.1867880601 |
| GSE54402 | Up | 0.1340688485 |
| GSE9593 | Down | -0.3350448542 |
| GSE43922 | Down | -0.5545701468 |
| GSE24585 | Down | -0.3003933024 |
| GSE37065 | Down | -0.1157092307 |
| GSE28863_A1 | Up | 0.0327386064 |
| GSE28863_A2 | Down | -0.2342435310 |
| GSE28863_A3 | Down | -0.0894456033 |
| GSE28863_A4 | Up | 0.0539984478 |
| GSE48662 | Down | -0.0752232196 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003168 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT004208 | Microarray | Functional MTI (Weak) | 16822819 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
