HCSGD entry for AP3B1


1. General information

Official gene symbolAP3B1
Entrez ID8546
Gene full nameadaptor-related protein complex 3, beta 1 subunit
Other gene symbolsADTB3 ADTB3A HPS HPS2 PE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005765Lysosomal membraneIDAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0006622Protein targeting to lysosomeIEAbiological_process
GO:0006886Intracellular protein transportTASbiological_process
GO:0007596Blood coagulationIEAbiological_process
GO:0008089Anterograde axon cargo transportIEA ISSbiological_process
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0019903Protein phosphatase bindingIPImolecular_function
GO:0030123AP-3 adaptor complexIEAcellular_component
GO:0030665Clathrin-coated vesicle membraneIEAcellular_component
GO:0032438Melanosome organizationIMPbiological_process
GO:0048007Antigen processing and presentation, exogenous lipid antigen via MHC class IbIEAbiological_process
GO:0048490Anterograde synaptic vesicle transportIEA ISSbiological_process
GO:0051138Positive regulation of NK T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51177066220.36942545500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0091306390
GSE13712_SHEARDown-0.3427173935
GSE13712_STATICUp0.1174173192
GSE19018Up0.4519205475
GSE19899_A1Down-0.1166261346
GSE19899_A2Down-0.1939305274
PubMed_21979375_A1Down-0.3796900098
PubMed_21979375_A2Up0.0354510746
GSE35957Up0.1796669628
GSE36640Up0.2490133196
GSE54402Up0.0577305555
GSE9593Up0.4788296392
GSE43922Down-0.0345198762
GSE24585Down-0.1109325577
GSE37065Up0.0797088927
GSE28863_A1Up0.0970434017
GSE28863_A2Up0.2945047288
GSE28863_A3Down-0.6441638113
GSE28863_A4Down-0.1154271656
GSE48662Down-0.2668874603

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001387pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-214-3pMIMAT0000271MIRT024966Microarray;OtherFunctional MTI (Weak)19859982
hsa-miR-421MIMAT0003339MIRT039356CLASHFunctional MTI (Weak)23622248
hsa-miR-221-3pMIMAT0000278MIRT046907CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.