HCSGD entry for AP3B1
1. General information
| Official gene symbol | AP3B1 |
|---|---|
| Entrez ID | 8546 |
| Gene full name | adaptor-related protein complex 3, beta 1 subunit |
| Other gene symbols | ADTB3 ADTB3A HPS HPS2 PE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006622 | Protein targeting to lysosome | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | TAS | biological_process |
| GO:0007596 | Blood coagulation | IEA | biological_process |
| GO:0008089 | Anterograde axon cargo transport | IEA ISS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0030123 | AP-3 adaptor complex | IEA | cellular_component |
| GO:0030665 | Clathrin-coated vesicle membrane | IEA | cellular_component |
| GO:0032438 | Melanosome organization | IMP | biological_process |
| GO:0048007 | Antigen processing and presentation, exogenous lipid antigen via MHC class Ib | IEA | biological_process |
| GO:0048490 | Anterograde synaptic vesicle transport | IEA ISS | biological_process |
| GO:0051138 | Positive regulation of NK T cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5117706622 | 0.3694254550 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0091306390 |
| GSE13712_SHEAR | Down | -0.3427173935 |
| GSE13712_STATIC | Up | 0.1174173192 |
| GSE19018 | Up | 0.4519205475 |
| GSE19899_A1 | Down | -0.1166261346 |
| GSE19899_A2 | Down | -0.1939305274 |
| PubMed_21979375_A1 | Down | -0.3796900098 |
| PubMed_21979375_A2 | Up | 0.0354510746 |
| GSE35957 | Up | 0.1796669628 |
| GSE36640 | Up | 0.2490133196 |
| GSE54402 | Up | 0.0577305555 |
| GSE9593 | Up | 0.4788296392 |
| GSE43922 | Down | -0.0345198762 |
| GSE24585 | Down | -0.1109325577 |
| GSE37065 | Up | 0.0797088927 |
| GSE28863_A1 | Up | 0.0970434017 |
| GSE28863_A2 | Up | 0.2945047288 |
| GSE28863_A3 | Down | -0.6441638113 |
| GSE28863_A4 | Down | -0.1154271656 |
| GSE48662 | Down | -0.2668874603 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001387 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-214-3p | MIMAT0000271 | MIRT024966 | Microarray;Other | Functional MTI (Weak) | 19859982 |
| hsa-miR-421 | MIMAT0003339 | MIRT039356 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046907 | CLASH | Functional MTI (Weak) | 23622248 |
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