HCSGD entry for DIXDC1

1. General information

Official gene symbolDIXDC1
Entrez ID85458
Gene full nameDIX domain containing 1
Other gene symbolsCCD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0005938Cell cortexIBAcellular_component
GO:0007049Cell cycleIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0021695Cerebellar cortex developmentIBA IEAbiological_process
GO:0021799Cerebral cortex radially oriented cell migrationIEAbiological_process
GO:0021869Forebrain ventricular zone progenitor cell divisionIEAbiological_process
GO:0030177Positive regulation of Wnt signaling pathwayIEAbiological_process
GO:0030900Forebrain developmentIBAbiological_process
GO:0031435Mitogen-activated protein kinase kinase kinase bindingIBA IEAmolecular_function
GO:0032956Regulation of actin cytoskeleton organizationIEAbiological_process
GO:0043010Camera-type eye developmentIBAbiological_process
GO:0043015Gamma-tubulin bindingIDAmolecular_function
GO:0043025Neuronal cell bodyIBA IEAcellular_component
GO:0043234Protein complexIEAcellular_component
GO:0043679Axon terminusIBA IEAcellular_component
GO:0045665Negative regulation of neuron differentiationIEAbiological_process
GO:0046328Regulation of JNK cascadeIBAbiological_process
GO:0046330Positive regulation of JNK cascadeIEAbiological_process
GO:0050772Positive regulation of axonogenesisIBA IEAbiological_process
GO:0060071Wnt signaling pathway, planar cell polarity pathwayIRDbiological_process
GO:0070507Regulation of microtubule cytoskeleton organizationIEAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96379397060.02713977050.99999024730.3141081722

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5851330956
GSE13712_SHEARUp0.0017180958
GSE13712_STATICDown-0.1720832021
GSE19018Down-0.3147285098
GSE19899_A1Down-0.1850867678
GSE19899_A2Down-0.8393964371
PubMed_21979375_A1Down-0.2623717164
PubMed_21979375_A2Down-0.2238191676
GSE35957Up0.1941905421
GSE36640Up0.2482644414
GSE54402Down-0.3262982075
GSE9593Down-0.0126400826
GSE43922Down-0.2798041994
GSE24585Down-0.6007248524
GSE37065Up0.0057394536
GSE28863_A1Down-0.0948711296
GSE28863_A2Down-0.1230447948
GSE28863_A3Down-0.2265652089
GSE28863_A4Up0.0905543882
GSE48662Up0.1992513715

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT016151SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT051092CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.