HCSGD entry for APOL1

1. General information

Official gene symbolAPOL1
Entrez ID8542
Gene full nameapolipoprotein L, 1
Other gene symbolsAPO-L APOL APOL-I FSGS4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005254Chloride channel activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006821Chloride transportIDAbiological_process
GO:0006869Lipid transportIEAbiological_process
GO:0008203Cholesterol metabolic processIEAbiological_process
GO:0008289Lipid bindingIDA IEAmolecular_function
GO:0019835CytolysisIDAbiological_process
GO:0031224Intrinsic component of membraneICcellular_component
GO:0031640Killing of cells of other organismIDAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034364High-density lipoprotein particleIDAcellular_component
GO:0042157Lipoprotein metabolic processIEAbiological_process
GO:0045087Innate immune responseIDAbiological_process
GO:0055085Transmembrane transportIDAbiological_process
GO:1902476Chloride transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02235037040.57070312300.35731673741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3781170081
GSE13712_SHEARDown-0.2331110931
GSE13712_STATICUp0.8003970483
GSE19018Up0.1846685397
GSE19899_A1Down-0.0812659036
GSE19899_A2Up0.1638538819
PubMed_21979375_A1Down-0.6850618409
PubMed_21979375_A2Up0.0047644511
GSE35957Down-0.2926407942
GSE36640Up1.8162078384
GSE54402Down-0.1821433368
GSE9593Up0.9774394173
GSE43922Up0.0148474166
GSE24585Up0.2180490399
GSE37065Up0.6430234308
GSE28863_A1Up0.3724899265
GSE28863_A2Up1.0243328176
GSE28863_A3Down-0.0018892584
GSE28863_A4Up0.1054292486
GSE48662Up0.4841172750

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.