HCSGD entry for COPS3
1. General information
| Official gene symbol | COPS3 |
|---|---|
| Entrez ID | 8533 |
| Gene full name | COP9 signalosome subunit 3 |
| Other gene symbols | CSN3 SGN3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008180 | COP9 signalosome | IDA IEA | cellular_component |
| GO:0009416 | Response to light stimulus | TAS | biological_process |
| GO:0010388 | Cullin deneddylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8780142244 | 0.1238701759 | 0.9999902473 | 0.6771312357 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0630116760 |
| GSE13712_SHEAR | Down | -0.1243562751 |
| GSE13712_STATIC | Down | -0.0180119595 |
| GSE19018 | Down | -0.6514289718 |
| GSE19899_A1 | Up | 0.2419979360 |
| GSE19899_A2 | Down | -0.3549835291 |
| PubMed_21979375_A1 | Up | 0.1671846031 |
| PubMed_21979375_A2 | Down | -0.2907527740 |
| GSE35957 | Down | -0.4473390421 |
| GSE36640 | Down | -0.5463815901 |
| GSE54402 | Up | 0.1919582536 |
| GSE9593 | Down | -0.2834890101 |
| GSE43922 | Down | -0.0431068280 |
| GSE24585 | Down | -0.0282123705 |
| GSE37065 | Down | -0.0697789136 |
| GSE28863_A1 | Up | 0.1301120167 |
| GSE28863_A2 | Down | -0.0430992814 |
| GSE28863_A3 | Down | -0.0513912896 |
| GSE28863_A4 | Up | 0.1720803150 |
| GSE48662 | Down | -0.4471829423 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020767 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026041 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT041921 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043162 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043413 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043822 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050294 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051794 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
