HCSGD entry for DGKD

1. General information

Official gene symbolDGKD
Entrez ID8527
Gene full namediacylglycerol kinase, delta 130kDa
Other gene symbolsDGKdelta dgkd-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003951NAD+ kinase activityIEAmolecular_function
GO:0004143Diacylglycerol kinase activityIDA IEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayNASbiological_process
GO:0007205Protein kinase C-activating G-protein coupled receptor signaling pathwayIEA NASbiological_process
GO:0007275Multicellular organismal developmentNASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010033Response to organic substanceIDAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0016023Cytoplasmic membrane-bounded vesicleIDAcellular_component
GO:0016049Cell growthNASbiological_process
GO:0019932Second-messenger-mediated signalingNASbiological_process
GO:0019992Diacylglycerol bindingNASmolecular_function
GO:0030168Platelet activationTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0046339Diacylglycerol metabolic processIC NASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIDAmolecular_function
GO:0051260Protein homooligomerizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41317757680.36295215990.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1617535292
GSE13712_SHEARDown-0.0186339730
GSE13712_STATICDown-0.2091118278
GSE19018Up0.1673218315
GSE19899_A1Down-0.0716170613
GSE19899_A2Down-0.0242106631
PubMed_21979375_A1Up0.1958018133
PubMed_21979375_A2Up0.7422674748
GSE35957Down-0.0241559903
GSE36640Down-0.1673884666
GSE54402Up0.4449223477
GSE9593Down-0.7021258613
GSE43922Up0.1675636739
GSE24585Down-0.1858798972
GSE37065Down-0.2681149857
GSE28863_A1Up0.1192584287
GSE28863_A2Up0.3150772491
GSE28863_A3Up0.0906100579
GSE28863_A4Down-0.0802653183
GSE48662Down-0.0912071306

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Phosphatidyl serineDB00144 NUTR00048

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019754MicroarrayFunctional MTI (Weak)20215506
hsa-miR-877-5pMIMAT0004949MIRT037279CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-5pMIMAT0000680MIRT044251CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.