HCSGD entry for DGKE
1. General information
| Official gene symbol | DGKE |
|---|---|
| Entrez ID | 8526 |
| Gene full name | diacylglycerol kinase, epsilon 64kDa |
| Other gene symbols | DAGK5 DAGK6 DGK NPHS7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003951 | NAD+ kinase activity | IEA | molecular_function |
| GO:0004143 | Diacylglycerol kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007205 | Protein kinase C-activating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4044859884 | 0.8102002849 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0898669656 |
| GSE13712_SHEAR | Up | 0.0787560318 |
| GSE13712_STATIC | Down | -0.1358343292 |
| GSE19018 | Down | -0.3105236525 |
| GSE19899_A1 | Up | 0.0686163905 |
| GSE19899_A2 | Up | 0.0147802591 |
| PubMed_21979375_A1 | Up | 0.1125638999 |
| PubMed_21979375_A2 | Up | 0.0956858856 |
| GSE35957 | Up | 0.2213795097 |
| GSE36640 | Up | 0.3224314010 |
| GSE54402 | Up | 0.2408361216 |
| GSE9593 | Down | -0.1871448998 |
| GSE43922 | Up | 0.2868155279 |
| GSE24585 | Down | -0.1281140204 |
| GSE37065 | Up | 0.2578246877 |
| GSE28863_A1 | Down | -0.0703988366 |
| GSE28863_A2 | Up | 0.1953991093 |
| GSE28863_A3 | Down | -0.1628584389 |
| GSE28863_A4 | Up | 0.0205360849 |
| GSE48662 | Up | 0.0395194390 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039816 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
