HCSGD entry for ENC1
1. General information
| Official gene symbol | ENC1 |
|---|---|
| Entrez ID | 8507 |
| Gene full name | ectodermal-neural cortex 1 (with BTB domain) |
| Other gene symbols | CCL28 ENC-1 KLHL35 KLHL37 NRPB PIG10 TP53I10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0010499 | Proteasomal ubiquitin-independent protein catabolic process | IDA | biological_process |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0017148 | Negative regulation of translation | IDA | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0003908780 | 0.1046325975 | 0.0518261307 | 0.6207541131 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.5588731159 |
| GSE13712_SHEAR | Up | 0.8690690799 |
| GSE13712_STATIC | Up | 0.1134752078 |
| GSE19018 | Down | -0.5404241988 |
| GSE19899_A1 | Up | 3.1798098168 |
| GSE19899_A2 | Up | 3.1404931366 |
| PubMed_21979375_A1 | Up | 2.1128824912 |
| PubMed_21979375_A2 | Up | 3.2310253755 |
| GSE35957 | Up | 0.8483619766 |
| GSE36640 | Up | 1.4296193380 |
| GSE54402 | Up | 1.5068830192 |
| GSE9593 | Up | 0.4504532446 |
| GSE43922 | Up | 2.1927865721 |
| GSE24585 | Up | 0.1100509594 |
| GSE37065 | Down | -0.5326898153 |
| GSE28863_A1 | Down | -0.6124459074 |
| GSE28863_A2 | Down | -0.2826237190 |
| GSE28863_A3 | Up | 0.1180024181 |
| GSE28863_A4 | Down | -0.0901147182 |
| GSE48662 | Down | -0.6632184331 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024264 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026945 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037951 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
