HCSGD entry for AJUBA

1. General information

Official gene symbolAJUBA
Entrez ID84962
Gene full nameajuba LIM protein
Other gene symbolsJUB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000932Cytoplasmic mRNA processing bodyIDAcellular_component
GO:0001666Response to hypoxiaIDAbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003714Transcription corepressor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0005815Microtubule organizing centerIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005911Cell-cell junctionIDA IEAcellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016339Calcium-dependent cell-cell adhesionIEAbiological_process
GO:0030027LamellipodiumIEAcellular_component
GO:0030032Lamellipodium assemblyIEAbiological_process
GO:0030334Regulation of cell migrationIEAbiological_process
GO:0031328Positive regulation of cellular biosynthetic processIEAbiological_process
GO:0031334Positive regulation of protein complex assemblyIDAbiological_process
GO:0033673Negative regulation of kinase activityIEAbiological_process
GO:0034613Cellular protein localizationIEAbiological_process
GO:0035195Gene silencing by miRNAIMPbiological_process
GO:0035313Wound healing, spreading of epidermal cellsIEAbiological_process
GO:0035331Negative regulation of hippo signalingIDAbiological_process
GO:0043087Regulation of GTPase activityIEAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0043406Positive regulation of MAP kinase activityIEAbiological_process
GO:0045294Alpha-catenin bindingIDA IEAmolecular_function
GO:0046474Glycerophospholipid biosynthetic processIEAbiological_process
GO:0048041Focal adhesion assemblyIEAbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
GO:1900037Regulation of cellular response to hypoxiaIDAbiological_process
GO:2000637Positive regulation of gene silencing by miRNAIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97149900080.00251306180.99999024730.0988733931

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4701259449
GSE13712_SHEARUp0.8440014614
GSE13712_STATICUp0.3185672555
GSE19018Down-0.1092603964
GSE19899_A1Down-0.4773911920
GSE19899_A2Down-0.3287564732
PubMed_21979375_A1Down-0.8110963643
PubMed_21979375_A2Down-0.5634532553
GSE35957Up0.2048881326
GSE36640Down-0.4584796485
GSE54402Down-1.1959745620
GSE9593Down-0.3473299659
GSE43922Down-0.5496477748
GSE24585Down-0.0454288321
GSE37065Down-0.8348927943
GSE28863_A1Down-0.4980485568
GSE28863_A2Down-0.4377388161
GSE28863_A3Down-0.9452952104
GSE28863_A4Down-0.0414085671
GSE48662Down-0.0926214993

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-128-3pMIMAT0000424MIRT021880MicroarrayFunctional MTI (Weak)17612493
hsa-miR-10a-5pMIMAT0000253MIRT025601SequencingFunctional MTI (Weak)20371350
hsa-miR-196b-5pMIMAT0001080MIRT042680CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.