HCSGD entry for MAEL

1. General information

Official gene symbolMAEL
Entrez ID84944
Gene full namemaelstrom spermatogenic transposon silencer
Other gene symbolsCT128 RP11-102C16.1 SPATA35
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000785ChromatinIEAcellular_component
GO:0000902Cell morphogenesisIEAbiological_process
GO:0001741XY bodyIEAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDA ISScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0007129SynapsisIEAbiological_process
GO:0007140Male meiosisIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisISSbiological_process
GO:0008630Intrinsic apoptotic signaling pathway in response to DNA damageIEAbiological_process
GO:0009566FertilizationIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030849AutosomeIEAcellular_component
GO:0031047Gene silencing by RNAISSbiological_process
GO:0033391Chromatoid bodyIEAcellular_component
GO:0034587PiRNA metabolic processISSbiological_process
GO:0043046DNA methylation involved in gamete generationISSbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043186P granuleISScellular_component
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0046620Regulation of organ growthIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0071547PiP-bodyISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47546677940.90624543900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0385750416
GSE13712_SHEARDown-0.2487257429
GSE13712_STATICDown-0.0757458774
GSE19018Up0.1173368885
GSE19899_A1Up0.1304206384
GSE19899_A2Up0.0354958873
PubMed_21979375_A1Up0.1322322096
PubMed_21979375_A2Up0.0172206512
GSE35957Up0.1778423907
GSE36640Down-0.0646687679
GSE54402Up0.0990714819
GSE9593Up0.2011127146
GSE43922Up0.0153754784
GSE24585Up0.3523760018
GSE37065Up0.1168278685
GSE28863_A1Down-0.1448764673
GSE28863_A2Up0.0487938063
GSE28863_A3Up0.1321242445
GSE28863_A4Down-0.0031119721
GSE48662Down-0.0040836650

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.