HCSGD entry for ATG4C
1. General information
| Official gene symbol | ATG4C |
|---|---|
| Entrez ID | 84938 |
| Gene full name | autophagy related 4C, cysteine peptidase |
| Other gene symbols | APG4-C APG4C AUTL1 AUTL3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000045 | Autophagic vacuole assembly | IGI | biological_process |
| GO:0004197 | Cysteine-type endopeptidase activity | IMP | molecular_function |
| GO:0005576 | Extracellular region | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005829 | Cytosol | ISS | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0006612 | Protein targeting to membrane | ISS | biological_process |
| GO:0006914 | Autophagy | IEA IGI | biological_process |
| GO:0008233 | Peptidase activity | IDA | molecular_function |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9422821435 | 0.0529341932 | 0.9999902473 | 0.4340438941 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0403652341 |
| GSE13712_SHEAR | Down | -0.2564286770 |
| GSE13712_STATIC | Down | -0.2173839507 |
| GSE19018 | Down | -0.0396186089 |
| GSE19899_A1 | Up | 0.0505683300 |
| GSE19899_A2 | Down | -0.6512548018 |
| PubMed_21979375_A1 | Down | -0.0473909224 |
| PubMed_21979375_A2 | Down | -0.5501031230 |
| GSE35957 | Down | -0.2179612127 |
| GSE36640 | Down | -0.1850645474 |
| GSE54402 | Down | -0.1006865832 |
| GSE9593 | Down | -0.4682474713 |
| GSE43922 | Down | -0.0227349109 |
| GSE24585 | Up | 0.0735191115 |
| GSE37065 | Up | 0.0600100334 |
| GSE28863_A1 | Up | 0.1356460145 |
| GSE28863_A2 | Up | 0.2786760790 |
| GSE28863_A3 | Down | -0.7558023991 |
| GSE28863_A4 | Down | -0.2462425877 |
| GSE48662 | Down | -0.1459703178 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | MIRT052446 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
