HCSGD entry for ZNRF1
1. General information
| Official gene symbol | ZNRF1 |
|---|---|
| Entrez ID | 84937 |
| Gene full name | zinc and ring finger 1, E3 ubiquitin protein ligase |
| Other gene symbols | NIN283 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030672 | Synaptic vesicle membrane | IEA | cellular_component |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IEA ISS | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9222959272 | 0.0914747882 | 0.9999902473 | 0.5753184946 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0940883595 |
| GSE13712_SHEAR | Down | -0.3973807691 |
| GSE13712_STATIC | Up | 0.1138845633 |
| GSE19018 | Up | 0.4891708662 |
| GSE19899_A1 | Down | -0.4900067125 |
| GSE19899_A2 | Down | -0.1673713952 |
| PubMed_21979375_A1 | Down | -0.7760478592 |
| PubMed_21979375_A2 | Down | -0.2325477764 |
| GSE35957 | Up | 0.0267886956 |
| GSE36640 | Down | -0.3644114634 |
| GSE54402 | Down | -0.2853534707 |
| GSE9593 | Up | 0.3038730582 |
| GSE43922 | Down | -0.1314286074 |
| GSE24585 | Down | -0.1058059785 |
| GSE37065 | Up | 0.0804644769 |
| GSE28863_A1 | Down | -0.0075987759 |
| GSE28863_A2 | Down | -0.0346211941 |
| GSE28863_A3 | Down | -0.1933057521 |
| GSE28863_A4 | Up | 0.0773466402 |
| GSE48662 | Down | -0.0622389841 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046491 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
