HCSGD entry for PPP1R15B
1. General information
| Official gene symbol | PPP1R15B |
|---|---|
| Entrez ID | 84919 |
| Gene full name | protein phosphatase 1, regulatory subunit 15B |
| Other gene symbols | CREP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000164 | Protein phosphatase type 1 complex | IEA | cellular_component |
| GO:0004722 | Protein serine/threonine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006417 | Regulation of translation | IEA | biological_process |
| GO:0006983 | ER overload response | IEA | biological_process |
| GO:0042542 | Response to hydrogen peroxide | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4540883363 | 0.0439333270 | 0.9999902473 | 0.3942860893 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8189980730 |
| GSE13712_SHEAR | Up | 0.0261457832 |
| GSE13712_STATIC | Down | -0.0019056299 |
| GSE19018 | Down | -0.7182572225 |
| GSE19899_A1 | Up | 0.3411308104 |
| GSE19899_A2 | Up | 0.3585103487 |
| PubMed_21979375_A1 | Up | 0.7409378198 |
| PubMed_21979375_A2 | Up | 0.6716736992 |
| GSE35957 | Down | -0.0164174426 |
| GSE36640 | Down | -0.2435558938 |
| GSE54402 | Up | 0.2871037881 |
| GSE9593 | Down | -0.3824748262 |
| GSE43922 | Up | 0.2464288943 |
| GSE24585 | Up | 0.0413912490 |
| GSE37065 | Up | 0.0393126696 |
| GSE28863_A1 | Down | -0.3664762889 |
| GSE28863_A2 | Down | -0.3049522061 |
| GSE28863_A3 | Down | -0.7095346260 |
| GSE28863_A4 | Down | -0.6607941085 |
| GSE48662 | Up | 0.0158168806 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT016665 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020212 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024204 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028000 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031169 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039642 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045226 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
