HCSGD entry for AIFM2
1. General information
| Official gene symbol | AIFM2 |
|---|---|
| Entrez ID | 84883 |
| Gene full name | apoptosis-inducing factor, mitochondrion-associated, 2 |
| Other gene symbols | AMID PRG3 RP11-367H5.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0004174 | Electron-transferring-flavoprotein dehydrogenase activity | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IDA | cellular_component |
| GO:0005811 | Lipid particle | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008637 | Apoptotic mitochondrial changes | IDA NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030261 | Chromosome condensation | IDA | biological_process |
| GO:0050660 | Flavin adenine dinucleotide binding | IDA | molecular_function |
| GO:0097194 | Execution phase of apoptosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0277080962 | 0.9467333080 | 0.3862843220 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4072180363 |
| GSE13712_SHEAR | Up | 0.5847573833 |
| GSE13712_STATIC | Up | 1.0249628599 |
| GSE19018 | Down | -0.2279115427 |
| GSE19899_A1 | Down | -0.2679544739 |
| GSE19899_A2 | Up | 0.2168847799 |
| PubMed_21979375_A1 | Down | -0.3209802004 |
| PubMed_21979375_A2 | Up | 0.0315800493 |
| GSE35957 | Down | -0.2000941868 |
| GSE36640 | Up | 0.3428345078 |
| GSE54402 | Up | 0.7705149716 |
| GSE9593 | Up | 0.1711399689 |
| GSE43922 | Up | 0.0873108783 |
| GSE24585 | Up | 0.0145173047 |
| GSE37065 | Up | 0.1093123372 |
| GSE28863_A1 | Up | 0.1385275905 |
| GSE28863_A2 | Up | 0.1079935058 |
| GSE28863_A3 | Up | 0.2654937827 |
| GSE28863_A4 | Up | 0.2427916314 |
| GSE48662 | Up | 0.2445273661 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023966 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031880 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-140-3p | MIMAT0004597 | MIRT038645 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046525 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
