HCSGD entry for PARP10
1. General information
| Official gene symbol | PARP10 |
|---|---|
| Entrez ID | 84875 |
| Gene full name | poly (ADP-ribose) polymerase family, member 10 |
| Other gene symbols | ARTD10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003950 | NAD+ ADP-ribosyltransferase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0010847 | Regulation of chromatin assembly | IDA | biological_process |
| GO:0048147 | Negative regulation of fibroblast proliferation | IDA | biological_process |
| GO:0070212 | Protein poly-ADP-ribosylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3535835986 | 0.8749804339 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0293466950 |
| GSE13712_SHEAR | Up | 0.7149618052 |
| GSE13712_STATIC | Up | 0.3425046175 |
| GSE19018 | Down | -0.0276471380 |
| GSE19899_A1 | Down | -0.0505381528 |
| GSE19899_A2 | Up | 0.0449952450 |
| PubMed_21979375_A1 | Down | -0.2478577931 |
| PubMed_21979375_A2 | Down | -0.2260851844 |
| GSE35957 | Up | 0.0155226259 |
| GSE36640 | Up | 0.0277809777 |
| GSE54402 | Down | -0.0723281640 |
| GSE9593 | Up | 0.0381567386 |
| GSE43922 | Up | 0.1064618712 |
| GSE24585 | Up | 0.1908928442 |
| GSE37065 | Up | 0.1831409800 |
| GSE28863_A1 | Up | 0.0225267923 |
| GSE28863_A2 | Up | 0.1934984562 |
| GSE28863_A3 | Up | 0.1902681689 |
| GSE28863_A4 | Down | -0.0056922015 |
| GSE48662 | Up | 0.0690252998 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019078 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-421 | MIMAT0003339 | MIRT039387 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT045838 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
