HCSGD entry for SEMA7A
1. General information
| Official gene symbol | SEMA7A |
|---|---|
| Entrez ID | 8482 |
| Gene full name | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| Other gene symbols | CD108 CDw108 H-SEMA-K1 H-Sema-L JMH SEMAK1 SEMAL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IDA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA ISS | cellular_component |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0045773 | Positive regulation of axon extension | IDA | biological_process |
| GO:0050727 | Regulation of inflammatory response | IEA ISS | biological_process |
| GO:0060907 | Positive regulation of macrophage cytokine production | IEA ISS | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0060120018 | 0.4392942251 | 0.2047113842 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0057267421 |
| GSE13712_SHEAR | Up | 0.7396691314 |
| GSE13712_STATIC | Down | -0.0660963209 |
| GSE19018 | Up | 0.2193809392 |
| GSE19899_A1 | Up | 1.0785843617 |
| GSE19899_A2 | Up | 1.1862000379 |
| PubMed_21979375_A1 | Up | 1.1704974379 |
| PubMed_21979375_A2 | Up | 0.2996735355 |
| GSE35957 | Up | 0.3464758330 |
| GSE36640 | Down | -0.4699158186 |
| GSE54402 | Up | 1.7886560663 |
| GSE9593 | Up | 0.3807544388 |
| GSE43922 | Up | 0.9968421260 |
| GSE24585 | Up | 0.0516960190 |
| GSE37065 | Down | -0.5779100454 |
| GSE28863_A1 | Down | -0.9572221227 |
| GSE28863_A2 | Down | -0.4521831649 |
| GSE28863_A3 | Down | -0.1779496021 |
| GSE28863_A4 | Up | 0.2239653005 |
| GSE48662 | Up | 0.6347339876 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040303 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
